Production of the NV full-size vans ended in the middle of 2021, with sales continuing through the end of the year.Advances in medicine and an ever-increasing birth rate means that there are more of us on this planet than ever before - this might not be so great for our freshwater sources and the general wellbeing of our world, but for large passenger vans such as the Nissan NV Passenger, things couldn't look any brighter. In 2020, Nissan reevaluated its commercial van business in North America, and decided to replace it with a 'Business Advantage' program for its other vehicles. The NV Passenger has a rollover risk of 30.6%. The NV3500 came in S, SV, or SL trim levels with no high roof available. Unusually, the latter was offered either with a V6 or a V8, unlike its V8-only cargo counterpart. It was also the only weight class offered in passenger van configuration (with up to 12 seats).

Payload capacity is 3,925 lb (1,780 kg), similar to the GMC/Chevrolet cargo van using the same '3500' designation, and informally known as a 'one-ton'.

The NV3500 HD was the heaviest weight class offered, and was only available with the large 5.6-litre V8 engine with either a low or a high roof. The SV trim featured a lockable center console with power outlets as well as an additional 120 V outlet in the cargo compartment along with the features from the 1500 SV, while the SL trim added chrome bumpers, grille, and door handles and 17' chrome wheels. It came in S, SV, or SL trim levels and was available in low or high roof the SL was only available with the V8. The payload is 3,142 lb (1,425 kg), similar to the GMC/Chevrolet cargo van using the same '2500' designation, and informally known as a 'three-quarter-ton'. The NV2500 HD (HD for 'heavy duty') was equipped with the 4-litre V6 engine, with the bigger V8 available as an option. It was available in S or SV trim, with the SV receiving power door locks, windows, outside mirrors, and 17' styled steel wheels. It was only available with the 4-litre V6. The NV1500 has a load capacity of 2,590 lb (1,175 kg), similar to the GMC/Chevrolet cargo van using the same '1500' designation, and informally known as a ' half-ton'. The V8-engined versions are also electronically limited to a top speed of 100 mph (161 km/h). The NV was not targeted directly at the (mainly fleet) buyers of the Ford E-Series and Chevrolet Express, but rather at private buyers including contractors and small business owners who are looking for a vehicle that is both capable and comfortable. The NV was also only available with rear-wheel drive, coupled to a five-speed automatic transmission (later also a seven-speed). The NV used the same F-Alpha platform as does the Nissan Titan full-size pickup, but due to the need for a flat loading floor it is highly modified and they end up sharing mainly powertrain pieces and some of the design language. The NV nameplate was previously used by a small pickup truck sold in Thailand.

Until the introduction of the Nissan NV, Mexico was the only country in North America selling a full-size Nissan van, as the Nissan Urvan was sold there. It was developed and marketed for the United States and Canada, where Nissan had not previously been present in the full-size segment.

The Nissan NV (Nissan Van) is a full-size van produced by Nissan from 2011 to 2021.

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